Reversible ischaemic neurological deficit associated with short-term methylphenidate medication.

Methylphenidate is a central nervous system stimulant pharmacologically related to amphetamines frequently used in attention deficit hyperactivity disorder (ADHD) and narcolepsy. Haemorrhagic stroke is a rare but well-known potential side-effect of amphetamine abuse, however, cerebral ischaemia has been reported casuistically (Rothrock et al., 1988). Here, we present incidence of a reversible ischaemic neurological deficit during short-term methylphenidate treatment.